Fear Conditioning System

Advantage

• The stimulus sound volume and frequency can be calibrated before each experiment by given a target decibel level.

• Accurate software analysis, real-time warning of animal freezing.

• Software can evaluate the freezing status in real time.

• White noise stimulus is available.

• Video, animal status, score and stimulus status can be display in the same time, accurate and direct-viewing.

Features

Sound

• Speaker: Raise and lower volume based on intrachamber volume (from the detector).

• AI detection, real time sound intensity (in dB) display in PC.

• White Noise Generator included in default Software, include White Noise and NWhiteNoise.

• White Noise: 1-130dB, Step 1dB, duration 0-180s.

• Pure sound stimulus: frequency 100Hz-18KHz, 1-130dB, Step 1dB, duration 0-180s.

Light Cues

• Visible and IR light dual bulb.

• Range 0-100Lux, Duration 0-180s.

Shock Grid

• 0.1-4.0mA in 0.1mA steps, during 0-9000min.

• DC Current.

• Removable Grid.

• Start and stop is controlled by software or manually.

Contextual Plates

• Easy to replace acrylic plates with multiple contexts allow for contextual learning experiments. 

• Default Patterns.

• Grey, White, Black, Chessboard, Vertical Stripes.

Software

• Independent signal detection control in each chamber to precise detect the signal in the experiment.

• Independent software operated for separated channel.

• Data can be exported to .csv or.doc format for further analysis.

Fear Conditioning Chamber

• Main Controller: 22 x 23 x 66cm (width x depth x height).

• Secondary Controller: 22 x 23 x 66cm (width x depth x height).

• Dimension: mouse 17 x 17 x 35cm, rat 25 x 25 x 35 cm (width x depth x height).

• Acrylic cage – four walls, no top, no base.

• Sound attenuation cubicle: 51 x 48 x 63 cm (width x depth x height).

• Sound attenuation cubicle is equipped with fan which can be start and stopped by software.

• Removable feces and urine tray for easy cleaning.

Data Record

• Duration of the experiment                                • First Freezing duration

• Number of Freezing                                           • Longest freezing start time

• Duration of Freezing                                          • Longest freezing duration

• Percentage of freezing time                               • Shortest freezing start time

• First Freezing time                                             • Shortest freezing duration

Fear Conditioning Operation

Ordering Information

Reference of Fear Conditioning System (some)

1.The synergistic effect of curcumin and mitoquinol mesylate on cognitive impairment and the neuropathology of Alzheimer's disease

2. Age-related LRRK2 G2019S Mutation Impacts Microglial Dopaminergic Fiber Refinement and Synaptic  Pruning Involved in Abnormal Behaviors

3. Comparative Proteomic Analysis Reveals the Effect of Selenoprotein W Deficiency on Oligodendrogenesis in F

ear Memory

https://www.mdpi.com/2076-3921/11/5/999

4. Periodontitis-induced neuroinflammation impacts dendritic spine immaturity and cognitive impairment

Periodontitis‐induced neuroinflammation impacts dendritic spine immaturity and cognitive impairment - Xie - 2024 - Oral Diseases - Wiley Online Library